evaluation of applying Plasma rich growth factor(PRGF) with Metformin gel 1% in treating periodontal intrabony defects
Phase 3
- Conditions
- Chronic periodontitis.
- Registration Number
- IRCT20100427003813N6
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
At least 18 years old
Chronic periodontal diseas with with two wall intabony defects
Similar plaque index(under 15%)
??Ability to maintaing oral hygiene
Signing of consenting form
Exclusion Criteria
Pregnancy
Existing of coagulation problems
use of drugs which interact with platellet
use of drugs which interact with wound healing
Allergy to surgical materials
Infective disease( Hepatitis, AIDS, Tuberclosis)
Any topical or systemic disease which containdicated to periodontal treatment
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Radiologic outcomes. Timepoint: at the beginning of study and 6 months after study. Method of measurement: parallel technic by means of digital sensor size 2(Soredex.Helsinki-finland)by Rinndentsply film holder.;Vertical clinical attachment level. Timepoint: at the begining of study and immediately before surgery, 3 and 6 months after sergury. Method of measurement: with perodontal probe.;Gingival index. Timepoint: at the beginning of study, immediately before sugery. Method of measurement: absevational (sillness & Loe).;VPD(vertical probing depth). Timepoint: at the beginning of study, immediately before sugery. Method of measurement: with perodontal probe.
- Secondary Outcome Measures
Name Time Method