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临床试验/CTRI/2024/04/065380
CTRI/2024/04/065380招募中不适用

Incidence and predictors of difficult mask ventilation and intubation in patients scheduled for coronary artery bypass surgery – a prospective observational study

Dr Aneesha Chris Wilfred1 个研究点 分布在 1 个国家目标入组 175 人开始时间: 2024年4月17日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
175
试验地点
1
主要终点
To determine the incidence of difficult mask ventilation and intubation in patients undergoing coronary artery bypass surgery using difficult mask ventilation grading and Intubation difficulty scale

研究概览

简要总结

Difficult airway is defined as ‘’the clinical situation in which a conventionally trained anesthesiologist experiences difficulty with face mask ventilation of the upper airway, difficulty with tracheal intubation or both.’’ Predictors of difficult airway include age, sex, BMI, ASA classification, external signs like, facies, facial hair, body habitus, head and neck pathology, airway examination including cervical spine mobility ,dentition, thyromental distance, sternomental distance, jaw protrusion, mallampatti classification, neck circumference, history of snoring.

 Patients undergoing coronary artery bypass grafting invariably have physiologically low cardiac reserve. They are also mostly associated with obesity, diabetes mellitus, hypertension, metabolic syndrome making them difficult airways. Duration of successful intubation (DSI) in these high risk patients should be less in order to prevent adverse events on myocardial oxygenation while securing the airway. Therefore it is essential to preoperatively clinically assess the airway and determine the predictors of difficult mask ventilation and intubation. In  this study we also assess the correlation of our clinical prediction with real time mask ventilation and intubation.

 The ASA originally defined difficult intubation as requiring more than 3 attempts or taking  longer than 10 minutes to complete using conventional laryngoscopy.

In order to assess difficult tracheal intubation and difficult mask ventilation there are scales of difficulty. Difficult mask ventilation grading includes usage of airway adjuncts, 2 hand technique, usage of muscle relaxant. Intubation difficulty scale includes 7 contributors namely, number of supplementary attempts, number of supplementary operators, alternative techniques used, glottic exposure (Cormack and lehane grading), lifting force applied during laryngoscopy, necessity of external laryngeal pressure and position of the vocal cords. Duration of successful intubation is also taken into account.

Patients undergoing coronary artery bypass graft surgery can have higher incidence of difficult airway. Awareness about the incidence and predictors of difficult airway in CABG patients will help the anesthesia provider in being adequately prepared for management of a difficult airway situation thereby reducing the laryngoscopy related adverse events on myocardial oxygenation.

 Hence in this observational study we will be clinically assessing the airway of patients undergoing coronary artery bypass surgery preoperatively and determine the difficulty of mask ventilation and intubation.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • 1.Age between 18 to 70 years 2.ASA 3 and ASA 4 patients undergoing Coronary Atery Bypass Grafting (CABG) 3.BMI more than 18 4.Ability to understand protocol and give informed consent.

排除标准

  • 1.Patients who are planned for Rapid Sequence Induction (RSI) 2.Patients who are on tracheostomy tube 3.Pregnant patients 4.Patients who do not consent for the study.

结局指标

主要结局

To determine the incidence of difficult mask ventilation and intubation in patients undergoing coronary artery bypass surgery using difficult mask ventilation grading and Intubation difficulty scale

时间窗: At the time of induction of anesthesia in the operation theatre

次要结局

  • To identify the predictors of difficult mask ventilation and intubation in patients undergoing coronary artery bypass surgery

研究者

发起方
Dr Aneesha Chris Wilfred
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Aneesha Chris Wilfred

Christian Medical College

研究点 (1)

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