Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?

Not Applicable

• Conditions: Infertility; Assisted Reproductive Technology; IVF

• Registration Number: NCT03756857
• Lead Sponsor: Acibadem Kadiköy Hospital

Brief Summary

Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique

Detailed Description

Eligible patients will be informed about the possibility of participating in the clinical trial in the beginning of treatment and on the day ET, a signed consent form will be collected from those recipients who confirmed their participation. These patients will be randomized immediately before the ET procedure by sequentially numbered, opaque, sealed envelopes

Study Timeline

• Study First Submitted: 2018-11-27
• Study First Submitted QC: 2018-11-27
• Study First Posted: 2018-11-28
• Study Start: 2019-01-21
• Status Verified: 2021-03
• Last Update Submitted: 2021-03-21
• Last Update Posted: 2021-03-23
• Primary Completion: 2021-09
• Study Completion: 2021-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

1. Patient has given written informed consent
2. BMI 18-30 kg/m2
3. < 2 previous failed IVF trials
4. At least two good quality embryos on the day of transfer

Exclusion Criteria

1. Congenital uterine anomaly
2. Untreated endometrial polyp or fibroid distorting uterine cavity
3. Presence of hydrosalpinx 4.2 or more prior IVF trial failure

5.Moderate to severe endometriosis 6.Recurrent pregnancy loss history

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
clinical pregnancy rate	5-6 weeks after embryo transfer	the presence of gestational sac on ultrasound

Secondary Outcome Measures

Name	Time	Method
implantation rate	3-4 weeks after embryo transfer	the number of gestational sacs divided by the number of embryos transferred

Trial Locations

Locations (1)

Acibadem Altunizade Hospital, Unit of ART; 🇹🇷 İstanbul, Turkey