Transcranial Direct Current Stimulation in pain control in patients with Rheumatoid Arthritis: a randomized, placebo-controlled, double-blind, phase II clinical trial

niversidade Federal do Amazonas0 sitesApril 25, 2022

Overview

No summary available.

Registry

who.int

Start Date

April 25, 2022

End Date

May 5, 2023

Last Updated

2 years ago

Study Type

Intervention

Sponsor

niversidade Federal do Amazonas

•Adult volunteers (higher than 18 years) diagnosed with Rheumatoid Arthritis; both genders; with chronic pain longer than 12 weeks or 3 months; with a pain level greater than 7 by the visual analog scale of Pain and who are using synthetic disease\-modifying drugs

•Volunteers who are using biological disease\-modifying drugs; who have neuropsychiatric diseases; who have a history of illicit drug use and abuse; who have neurological, cognitive, or motor deficits; who underwent neurosurgical interventions (craniotomy); who have a clinical diagnosis of severe depression with more than 30 points according to the Beck Depression Inventory tool; who have a history of seizures and/or epilepsy; who are using high doses of opioids (more than 30 mg of Oxycodone, Hydrocodone or 7\.5 mg of Hydromorphone or equivalent drug); pregnant women; who have metallic implants in the cranial and/or facial region; who use a pacemaker; with a history of skin diseases; who have other autoimmune diseases not related to Rheumatoid Arthritis; who have cancer diseases; who have disease in the decompensated phase (ischemic heart disease, kidney and/or liver diseases)