A comparative, observational study to evaluate the effect of narrow band UV-B therapy in patients with progressive non-segmental vitiligo versus non-progressive non- segmental vitiligo.

All India Institute of Medical Sciences0 个研究点目标入组 30 人开始时间: 待定最近更新: 2021年11月24日

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•1.Patients of either sex, aged 15-60 years with a clinical diagnosis of non-segmental vitiligo with any of the following features â??
•a. Involving >5 % BSA
•b. Involving 2-5 % BSA, but multi-focal, scattered lesions confined to non-contiguous areas of the body
•2. With no systemic and no topical treatment for 1 month.
•3. These patients will be divided into two groups.
•a. Progressive vitiligo - >5 new lesions in past 1 month or >15 new lesions in past 3 months,
•b. Non-progressive vitiligo - no new lesions in the past 6 months.

•1) Segmental vitiligo
•2) Vitiligo involving > 50 % BSA
•3) Pregnant and lactating females
•4) History of photosensitivity / photo-aggravated dermatomes like SLE, xeroderma pigmentosum, basal cell nevus syndrome, prior history of skin carcinoma, photosensitive disorders, contact photosensitive substances, photosensitizing medications with an action spectrum with the corresponding UVA or UVB wave-lengths etc.
•5) Inability to attend dermatology clinic for 3 sessions per week (or at least 2 sessions per week) for NB-UVB phototherapy
•6) Lip-tip vitiligo or acrofacial variant only with tips of fingers and toes and lip involvement
•7) Pure mucosal vitiligo
•8) Patients with immuno-compromised states, like HIV/AIDS etc.
•9) Patients with malignancies (cutaneous and internal)

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