An observational study on patients with non-segmental vitiligo patients on NB-UVB and to look for effect on progression of the disease.

Not Applicable

• Conditions: Health Condition 1: null- Vitiligo

• Registration Number: CTRI/2016/04/006809
• Lead Sponsor: All India Institute of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

1.Patients of either sex, aged 15-60 years with a clinical diagnosis of non-segmental vitiligo with any of the following features â??

a. Involving >5 % BSA

b. Involving 2-5 % BSA, but multi-focal, scattered lesions confined to non-contiguous areas of the body

2. With no systemic and no topical treatment for 1 month.

3. These patients will be divided into two groups.

a. Progressive vitiligo - >5 new lesions in past 1 month or >15 new lesions in past 3 months,

b. Non-progressive vitiligo - no new lesions in the past 6 months.

Exclusion Criteria

1) Segmental vitiligo

2) Vitiligo involving > 50 % BSA

3) Pregnant and lactating females

4) History of photosensitivity / photo-aggravated dermatomes like SLE, xeroderma pigmentosum, basal cell nevus syndrome, prior history of skin carcinoma, photosensitive disorders, contact photosensitive substances, photosensitizing medications with an action spectrum with the corresponding UVA or UVB wave-lengths etc.

5) Inability to attend dermatology clinic for 3 sessions per week (or at least 2 sessions per week) for NB-UVB phototherapy

6) Lip-tip vitiligo or acrofacial variant only with tips of fingers and toes and lip involvement

7) Pure mucosal vitiligo

8) Patients with immuno-compromised states, like HIV/AIDS etc.

9) Patients with malignancies (cutaneous and internal)

Study & Design

• Study Type: Observational
• Study Design: Not specified