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Colonoscopy with EndoCuff vs conventional colonoscopy: A randomized controlled trial.

Conditions
-colonoscopy -colorectal cancer (CRC) -adenomas, adenoma miss rate -disposable device, the EndoCuff-adenoma detection rate (ADR)-mean number of adenomas per patient (MAP)In Dutch:-colonoscopiecolorectaal carcinoom-adenomen-hulpmiddel: Endocuff-adenoom detectie rate (ADR)
Registration Number
NL-OMON20756
Lead Sponsor
Academic Medical Centre
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
972
Inclusion Criteria

1. Aged 45 years and older;

2. Scheduled for colonoscopy for on of the following indications: polyp surveillance, changed bowel habits and/or
bloody stools or bowel complaints, FOBT+ screening, positive family history for CRC, abdominal pain;

Exclusion Criteria

1. Polyposis syndromes;

2. Inflammatory bowel disease (active disease or surveillance);

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Mean number of adenomas per patient;<br /><br>2. Adenoma detection rate (percentage of colonoscopies where at least one adenoma is found).
Secondary Outcome Measures
NameTimeMethod
1. Polyp detection rate & number of polyps per patient;<br /><br>2. Flat adenoma detection rate;<br /><br>3. Polyp retrieval rate;<br /><br>4. Cecal intubation rate and cecal intubation time;<br /><br>5. Discomfort during the procedure using the Gloucester Comfort scale;<br /><br>6. Subjective difficulty of the procedure as assessed by the endoscopist;<br /><br>7. Complication rate.
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