Standard versus high definition colonoscopy.
- Conditions
- adenomascreening colorectal cancercolonoscopy
- Registration Number
- NL-OMON20419
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 1472
Inclusion Criteria
A. One of the following reasons for colonoscopy:
1. Abdominal complaints;
Exclusion Criteria
1. Previous extended colon surgery;
2. Inflammatory bowel disease (IBD);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adenoma detection rate (ADR): The total number of adenomatous lesions (histological proven) divided by the number of patients per arm in all four groups.
- Secondary Outcome Measures
Name Time Method 1. The total number of polyps (adenomatous polyps, hyperplastic polyps, serrated adenomas and inflammatory polyps);<br /><br>2. The total number and percentage of non-polypoid or flat adenomas (Paris classification 0-IIa-c);<br /><br>3. Proportion of patients with adenoma;<br /><br>4. Proportion of patients with more than one polyp;<br /><br>5. The total number and percentage of small polypoid (< 5mm) or flat lesions (height < ½ diameter);<br /><br>6. The total number of advanced adenoma defined as adenoma with high grade dysplasia, villous components, intramucosal carcinoma and angio-invasive growth;<br /><br>7. Number of missed lesions. This will be assessed after a follow up period of 60 months. Patients will be asked by a questionnaire whether they have had any colonoscopy within 60 months of the study period and if so, if any (pre)malignant lesions are found.<br>