Effect of TSH Level on adverse Outcome of Pregnancy in Subclinical Hypothyroidism
Phase 3
Recruiting
- Conditions
- Subclinical hypothyroidism.Subclinical iodine-deficiency hypothyroidism
- Registration Number
- IRCT20180314039091N1
- Lead Sponsor
- Zanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
Pregnant women with TSH levels ranging from 2.5 to 9.3 in the first trimester of pregnancy and TSH levels between 3 to 1.4 in the second and third trimesters
Their free T4 levels are within the normal range
Thyroid size is normal in the examination, and the nodule or mass is not touched
Pregnant women who do not have a history of thyroid disease
Do not have a history of Pregnancy Loss.
There is no history of thyroid surgery
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pregnancy Loss. Timepoint: Until 20 weeks for abortion and until delivery for IUFD and Fetal Loss. Method of measurement: check list.;Eclampsia. Timepoint: During pregnancy care. Method of measurement: Sphygmomanometer.;Neonatal death. Timepoint: Delivery. Method of measurement: check list.;11/5000Showing translation for ????? ?????Translate instead ????? ?????Apgar lower. Timepoint: Delivery. Method of measurement: Apgar score.;Preterm Labour and Delivery. Timepoint: From 20 to 37 weeks of pregnancy. Method of measurement: Check list.;Intra Uterim Growth Restrection. Timepoint: During pregnancy. Method of measurement: Ultrasound.;Premature rupture of membranes. Timepoint: Third Trimsters Pregnancy. Method of measurement: Chek list.;Placenta previa - premature separation of pelacenta - abruptio placenta. Timepoint: Pregnancy. Method of measurement: Chek list.
- Secondary Outcome Measures
Name Time Method Thyroid hormones(FT4 - T4 - TSH - TOP Ab). Timepoint: Until the 20th of every month and then at week 32 to 36. Method of measurement: T4 and TSH (ECL method) FT4 and TPO Ab (ICMA method).