Investigation of the sensitivity of hypothalmic dopamine receptors using amisulpiride in healthy young men

Department of Health (UK)0 个研究点目标入组 20 人开始时间: 2003年9月12日最近更新: 2016年10月17日

试验速览

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•A total of 20 male subjects aged 18-30, will be recruited from the population of the University. All subjects will be healthy non-smokers. Posters advertising the study will be displayed around the University of Birmingham and individuals expressing an interest in the study will be given a subject information sheet and have the study explained to them by one of the investigators. Suitable subjects wishing to participate in the study will complete a general health questionnaire and sign a consent form. It will be made clear that subjects are free to withdraw from the study at any time.

•1. Volunteer suffers from cardiovascular disease
•2. Volunteer has/is suffering from an infection or is on medication
•3. Volunteer has asthma
•4. Volunteer has epilepsy or a predisposing condition
•5. Volunteer has a history of kidney disease
•6. Volunteer has a history of Parkinson's disease
•In addition to the health questionnaire, volunteers will undergo an independent medical screening with Professor MJ Kendall before entering the study to ensure that there are no underlying general health problems or psychological reasons that contraindicates a neuroendocrine challenge with amisulpiride.

发起方

Department of Health (UK)