NL-OMON39683RecruitingPhase 3
Multi Center Clinical trial of endovascular treatment of acute ischemic stroke in the Netherlands. - MR CLEA
Erasmus MC, Universitair Medisch Centrum Rotterdam0 sites500 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Enrollment
- 500
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •*A clinical diagnosis of acute stroke, with a deficit on the NIH stroke scale of more than 2 points.
- •CT or MRI scan ruling out intracranial hemorrhage.
- •Intracranial arterial occlusion of the distal intracranial carotid artery or middle (M1/M2) or anterior (A1/A2) cerebral artery, demonstrated with CTA, MRA or DSA.
- •The possibility to start treatment within 6 hours from onset.
- •Informed consent given.
- •Age 18 or over.
Exclusion Criteria
- •- cerebral infarction in past 6 weeks
- •-history in intracerebral bleeding
- •-RR > 185/110 unresponsive to antihypertensive agents
- •-blood glucose of < 2.7 or > 22.2
- •-Clinical signs of hemorrhagic diathesis or platelet count <90 x 10*9/L, APTT>50 sec or INR >1.7
- •- intravenous treatment with thrombolysis with a dose exceeding 0.9mg/kg or 90 mg
- •-patients who are treated with intravenous thrombolysis while having cantra-indications for it.;Exclusion criteria for mechanical thrombectomy
- •- carotid artery stenosis over 70% (NASCETT) which cannot be stented
- •-RR > 185/110
- •-Blood glucose < 2.7 or >22.2
- •-INR > 3.0 or platelet count < 40 x 10*9
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