Foot Perfusion by Dynamic Contrast Enhanced MRI in Patients With Peripheral Artery Disease
Not yet recruiting
- Conditions
- Peripheral Arterial DiseasePerfusion
- Interventions
- Diagnostic Test: DCE MRI
- Registration Number
- NCT06525415
- Lead Sponsor
- Fudan University
- Brief Summary
We investigate the peri-operative foot perfusion through dynamic contrast enhanced MRI in patients with peripheral artery disease
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- 18 to 80 years old;
- PAD patients with Fontaine grade II-IV or Rutherford grade 2-6 and underwent a successful revascularization;
- Patients completed both pre- and post-operative MRI workups;
- Patients signed the informed consent form and be able to complete the clinical follow-up for 1 months.
Exclusion Criteria
- Patients has participated in other clinical studies;
- Patients with Heart failure (NYHA III/IV)/right to left shunt heart disease/ severe aortic and mitral insufficiency/acute coronary syndrome/malignant arrhythmia/severe pulmonary hypertension (pulmonary artery pressure at least 90 mmHg)/moderate to severe renal insufficiency (creatinine clearance rate<60 ml/min)
- Any allergic constitution;
- Pregnancy and childbirth;
- Life expectancy<12 months.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description PAD group DCE MRI patients of peripheral artery disease who underwent endovascular treatment
- Primary Outcome Measures
Name Time Method preoperative perfusion parameters Between Aug.1 2024 and OCT.31 2024 preoperative perfusion parameters by dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI)
- Secondary Outcome Measures
Name Time Method survival Between Aug.1 2024 and NOV.30 2024 ankle brachial index Between Aug.1 2024 and OCT.31 2024 clinical success Between Aug.1 2024 and NOV.30 2024