NCT00177762已完成1 期
Dose-Response of Exercise on Long-Term Weight Loss
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- weight loss
研究概览
简要总结
The purpose is to examine varying durations and intensities of exercise on long-term weight loss.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •21-45 years of age
- •BMI = 27-40 kg/m2
- •Ability to provide informed consent.
- •Ability to provide consent from their personal physician to participate in this study.
排除标准
- •Reporting regular exercise participation of at least 20 minutes per day on at least 3 days per week during the previous six months. (This study is designed to recruit relatively sedentary adults.)
- •Diabetes, hypothyroidism, or other medical conditions which would affect energy metabolism.
- •Currently pregnant, pregnant within the previous six months, or planning on becoming pregnant within the next 24 months. (Pregnancy will be based on self-report and will be included on the detailed medical history that is completed by subjects.)
- •Non-medicated resting systolic blood pressure >160 mmHg or non-medicated resting diastolic blood pressure >100 mmHg, or taking medication that would affect blood pressure.
- •Taking medication that would affect resting heart rate or the heart rate response during exercise (e.g., beta blockade).
- •Arrhythmia on resting or exercise electrocardiogram that would indicate that vigorous exercise was contraindicated.
- •History of myocardial infarction or valvular disease.
- •History of orthopedic complications that would prevent optimal participation in the exercise component (e.g., heel spurs, severe arthritis).
结局指标
主要结局
weight loss
次要结局
- fitness
- dietary intake
- physical activity
- mediators
- body composition
研究者
研究点 (2)
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