COVID-19 Testing in Patients With Vascular Disorders

Completed

• Conditions: Covid19
• Interventions: Diagnostic Test: PCR

• Registration Number: NCT04838093
• Lead Sponsor: Medical University of Vienna

Brief Summary

Background: To investigate the prevalence of SARS-CoV-2 infection in hospitalized patients with vascular disorders after implementing institutional and governmental safety measures.

Materials and Methods: Vascular patients (VPs) admitted to our tertiary care hospital were routinely tested for SARS-CoV-2 infection on a two days basis between March and December, 2020. The prevalence of SARS-CoV-2 was compared between VPs and two independent Austrian populations (April and November 2020) tested by the Austrian Ministry of Science. The results were also compared to a cohort of health care personnel (HCP) working in close proximity to the study patients, tested weekly, between March and December, 2020. RT-PCR and antigen test were used to detect SARS-CoV-2.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-01
• Primary Completion: 2020-12-01
• Study Completion: 2021-01-01
• Status Verified: 2021-04
• Study First Submitted: 2021-04-05
• Study First Submitted QC: 2021-04-07
• Last Update Submitted: 2021-04-07
• Study First Posted: 2021-04-08
• Last Update Posted: 2021-04-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2243

Inclusion Criteria

All inpatient admissions

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Exclusion Criteria

Outpatient admissions

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control cohort:	PCR	data of two nationwide PCR-based studies conducted in a representative random sample, from April 1-6, and November 12-14, 2020, collected by the Austrian Ministry of Science and the Austrian Red Cross to estimate the spread of SARS-CoV-2 infection among the non-hospitalized Austrian population.
HCP cohort:	PCR	HCP worker data, including nurses, nurse technicians, physicians, surgical personal, physical therapists, nurse practitioners, environmental service workers, administrative staff, and dietitians, working in close proximity to admitted patients at our tertiary care hospital from March 16 to December 07, 2020.
Patient cohort:	PCR	all patients with vascular disorders consecutively admitted at our tertiary care hospital from March 16 to December 07, 2020

Primary Outcome Measures

Name	Time	Method
prevalence of SARS-CoV-2 infection	March 16 to December 07, 2020	The primary endpoint of the present study was to determine the prevalence of SARS-CoV-2 infection in patients with vascular disease after the implementation of institutional and governmental safety measures and compared it to SARS-CoV-2 infections among the general population in Austria.

Trial Locations

Locations (1)

Medical University of Vienna; 🇦🇹 Vienna, Austria