IRCT2014062117684N5
Completed
Phase 2
The study of the effect of chewing sugar-free gums after recieving I-131, on I-131 absorbed dose and its side effects in the salivary glands of patients with differentiated thyroid cancer
Shiraz university of medical science, Vice chancellor for research0 sites60 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Shiraz university of medical science, Vice chancellor for research
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion Criteria:
- •1\-Patients older than 20 years for whom thyroidectomy has been performed for 4\-6 weeks prior to initiation of the study due to differenciated thyroid cancer and are referred to Namazi Hospital Center of Nuclear Medicine for ablative radioactive iodine \-131 therapy; 2\-Patients who have received low\-iodine diet for two weeks;
- •3\-Patients must be at hypothyroid state at the time of the study;
- •4\-Patients should have signed the informed consent form and should give permission for their participation in the study;
Exclusion Criteria
- •1\-Any positive history of previous salivary gland diseases;
- •2\-Any positive history of collagen tissue diseases;
- •3\-Positive history of Phenylketonuria;
- •4\-Positive history of using diuretics, Antihistamines, Antidepressants or Anticholinergic medications;
- •5\-Positive history of previously receiving Radiotherapy at Head \& Neck region;
- •6\-Positive history of previous treatment with radioiodine ( 131I );
- •7\-Difficulty in taking large amount of fluid;
Outcomes
Primary Outcomes
Not specified
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