Effects of Sugar-free Products With Added Sweeteners on Glycemic Responses

Not Applicable

Completed

• Conditions: Appetitive Behavior; Potential Abnormality of Glucose Tolerance

• Registration Number: NCT04857554
• Lead Sponsor: Agricultural University of Athens

Brief Summary

This study investigated the effects of three commonly used sugar-free snacks with added sweeteners on glycemic responses

Detailed Description

This study aimed at 1. to determine the glycemic index and glycemic load of three sugar-free products with added sweeteners: apricot jam, cranberry cereal bar, and cocoa drink, and 2. to investigate the effects of these products on the postprandial glycemic response in healthy subjects

Study Timeline

• Study Start: 2020-07-30
• Primary Completion: 2020-09-30
• Study Completion: 2020-09-30
• Status Verified: 2021-04
• Study First Submitted: 2021-04-21
• Study First Submitted QC: 2021-04-21
• Last Update Submitted: 2021-04-21
• Study First Posted: 2021-04-23
• Last Update Posted: 2021-04-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• healthy
• non-smoking
• non-diabetic men and women
• body mass index (BMI) between 18 and 29.9 kg/m2

Exclusion Criteria

• severe chronic disease (e.g. coronary heart disease, diabetes mellitus,kidney or liver conditions, endocrine conditions)
• gastrointestinal disorders
• pregnancy
• lactation
• competitive sports
• alcohol
• drug dependency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Capillary blood glucose responses	2 hours	Clinically useful change in blood glucose, defined as the restoration of glucose within normal limits during the 2hr glucose tolerance test

Secondary Outcome Measures

Name	Time	Method
Subjective appetite ratings	2 hours	Useful change in subjective appetite using visual analogue scales with a score 0 to 10 (given in the form of booklet,one scale per page) at baseline, 15, 30, 45, 60, 90 and 120 min. The minimum or maximum score will be evaluated if it is better or worse depending on the appetite variable e.g hunger, satiety, desire to eat etc.

Trial Locations

Locations (1)

Agricultural University of Athens; 🇬🇷 Athens, Attica, Greece