A Series of N-of-1 Randomized Trials of Chaixiong Qiwei formula for Tension-type Headache.
- Conditions
- Tension-type Headache
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1.Patients must meet the diagnostic criteria of Chronic tension- type headache;2.Clinical findings of CTTH for= 3 months and the number of TTH days=15 days in the previous month before screening;3.The onset of TTH should have happened before the age of 50 years;4.Patients aged between 18 and 65 years;5.Participants voluntarily participated in this study, signed informed consent.
1.TTH combined with migraine, cluster headache and other causes of headache;2.TTH with regular overuse of acute or symptomatic headache medication, including regular intake of drugs on=10 days/month for opioids and combination analgesics and on=15 days/month for paracetamol (also known as acetaminophen),acetylsalicylic acid and NSAID;3.Patients with severe liver and kidney dysfunction;serum transaminase levels and creatinine more than double the normal value;4.Patients combined with severe disease such as cardiovascular, nervous system, digestive system or hematopoietic system;5.Patients who have experienced alcohol or drug dependence in the last 6 months before screening;6.Patients with nervous system diseases affecting cognitive function, such as Alzheimer's disease, severe Parkinson's disease, encephalitis, etc;7.Patients who are pregnant or lactating, preparing for pregnancy during the trial;8.Patients who are allergic to research drugs and its ingredients( such as Bombyx batryticatus);9.Subjects participating in other clinical trials;10.Researchers estimate that the patient unable to complete the study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method