Interaction between motor fatigue and cognitive functioning in patients with multiple sclerosis
Completed
- Conditions
- Multiple sclerosis10012303
- Registration Number
- NL-OMON38018
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Relapsing-remitting multiple sclerosis
EDSS < 5,5
Sufficient hand function to operate the force recorder
Righthandedness
Informed consent
Exclusion Criteria
Psychiatric disorder
Depression
Neurological disorder other than MS
EDSS >= 5,5
Hearing disorder
Medication that influences (subjective) fatigue or force production (Amantadine, Amytryptiline, Pemoline, Tizanidine, Baclofen, Benzodiazepines, Potassium channel blockers, or modafinil. Or use of prednisolon in the past 6 weeks).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary parameters are the number of accurate responses to the CRT and the<br /><br>reaction times of these reactions.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Maximal voluntary contraction (MVC), decrease in force during fatigue.</p><br>