Macronutrients and energy of human milk in relation to the growth of preterm infants

• Conditions: Associations between macronutrients in human milk and preterm infant growth.; Preterm infant; Human milk; Macronutrients; Growth

• Registration Number: TCTR20230831003
• Lead Sponsor: The Ratchadapiseksompotch Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-31
• Last Update Posted: 19 August 2024
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

1.Preterm infants with GA not more than 34 weeeks or with birth weight not more than 1,800 grams
2. Preterm infants who receive human milk at least 80 to 100 ml/kg/day
3. Healthy mothers of preterm infants who can provide adequate human milk

Exclusion Criteria

1.Infants born with non-viable congenital anomalies or anomalies which affect infant growth such as neural tube defect, congenital heart disease, gastrointestinal tract abnormality
2. Infants with small for gestational age (SGA)
3.Preterm infants with length of hospital stay less than 7 days

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Preterm infant growth 1 week after preterm infants receive at least 80 to 100 ml/kg/day of human milk Body weight, Length ,Head circumference

Secondary Outcome Measures

Name	Time	Method
Preterm human milk macronutrients (Carbohydrate, protein, fat and energy) At the time when preterm infants receive human milk Human milk analyzer (MIRIS),To compare the expected macronutrient and energy intake of preterm infants using the reference-based calculation (Breastfeeding, 9thed.) and the data using the human milk analyzer-based calculation At the time when preterm infants receive human milk Human milk analyzer (MIRIS)