PRE-OCC study
Recruiting
- Conditions
- Obstructive colon cancer
- Registration Number
- NL-OMON26935
- Lead Sponsor
- Wetenschapsacademie Amphia
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 110
Inclusion Criteria
Patients 18 years or older.
- Patients presenting with symptoms of bowel obstruction caused by (high
suspicion or histologically proven) colonic cancer.
- Patients presenting with (partial) obstruction (abdominal pain, nausea, vomiting,
diarrhoea) confirmed by the presence of a dilated colon or ileum with a computed
tomography (CT-scan).
Exclusion Criteria
- Obstruction of the colon pathologically caused by benign disease.
- Obstruction of the colon caused by an extra-colonic malignancy.
- Suspicion of emergency complications caused by peritonitis due to perforation
(tumour or blow out) or sepsis.
- Rectal cancer
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complication-free survival (CFS) at 90 days after hospitalization. Complication is defined here as mortality and/or development of a major complication (Clavien-Dindo classification >2).
- Secondary Outcome Measures
Name Time Method Complications, creation of primary anastomosis, stoma creation, radical tumour resection, operative blood loss, operation time, total hospital stay (in total, after resection or reoperation), oncological resection. With a follow up of 1 year.