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Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients

Not Applicable
Completed
Conditions
Chest Pains
Registration Number
NCT00431886
Lead Sponsor
Seoul National University Bundang Hospital
Brief Summary

The purpose of this study is to determine the usefulness of 64 slice multi-detector computed tomography as a first diagnostic approach in acute chest pain patients in emergency room

Detailed Description

We prospectively enrolled the patients with acute chest pain who visited ED. Exclusion criteria were myocardial infarction (MI) with ST elevation, unstable vital sign, uncontrolled arrhythmia, renal dysfunction, hypersensitivity to contrast media and pregnancy. Patients were allocated into 3 categories based on history, physical exam, and electrocardiogram: 1) definite angina with uncertainty of regarding MI (high risk), 2) probable angina (intermediate risk), 3) low likelihood of angina (low risk), and then randomized to either receive MDCT immediately (MDCT group), or not (control). We compared diagnostic accuracy, length of stay in ER, admission rate, and major adverse cardiac events (MACE) and clinical diagnosis in 1 month after discharge from ED.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
400
Inclusion Criteria
  • Acute chest pain patient visiting emergency room
Exclusion Criteria
  • unstable vital sign
  • renal failure
  • ST elevation myocardial infarction
  • uncontrolled arrhythmia
  • hypersensitivity to contrast dye
  • clinically no possibility of angina

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Unnecessary admission rate
Admission rate
Secondary Outcome Measures
NameTimeMethod
MACE
Stay time in emergency department
Diagnostic accuracy

Trial Locations

Locations (1)

Seoul National University Bundang hospital

🇰🇷

Sungnam-si, Kyungkido, Korea, Republic of

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