A Randomised Controlled Trial on Recreational Runners With Patellofemoral Pain: Effects of Rehabilitation Approaches Based on Specific Underlying Mechanisms
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 69
- 试验地点
- 2
- 主要终点
- Changes in symptoms and function using a self-reported questionnaire, the Activities of Daily Living Scale of the Knee Outcome Survey (KOS-ADLS)
研究概览
简要总结
From a rehabilitation point of view, while several approaches exist to retrain runners with PFPS, it is not clear which one is most effective, or why. The goals of this randomised-controlled trial are: 1) to compare the effectiveness of three rehabilitation programs on pain and functional limitations of runners with PFPS and 2) to explain why the programs are effective or not based on laboratory analyses. After baseline evaluation, runners will be randomly assigned to one of three treatment groups, each with a specific 8-week rehabilitation program aimed at addressing the efficiency of a specific type of retraining. These groups are: 1) Control; 2) muscle recruitment; 3) reducing knee loading during running.
The investigators hypothesis is that the intervention targeting a reduction in knee loading will be significantly more effective in reducing symptoms and improving function of runners with patellofemoral pain syndrome.
详细描述
Hypothesis will be tested using symptoms and functional status questionnaires. In addition, mechanistic analyses will be conducted using a running assessment using an instrumented treadmill and kinematics analyses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Running mileage at least 15km
- •Symptoms since at least 3 months
- •Pain level at least 3/10 during running and 3 activities among: kneeling, squatting, stairs and resisted knee extension
- •Score lower than 85/100 on the KOS-ADLS
排除标准
- •History of knee surgery or patellar dislocation
- •Pain believed to originate either from meniscus or from patellar tendon
- •Pain following an acute trauma
- •Concurrent lower limb injuries
- •History of neurological, inflammatory, rheumatoid disease
结局指标
主要结局
Changes in symptoms and function using a self-reported questionnaire, the Activities of Daily Living Scale of the Knee Outcome Survey (KOS-ADLS)
时间窗: After 4 weeks and 8 weeks of rehabilitation; 3 months after the end of the rehabilitation program
A validated self-reported questionnaire (found to have the best psychometric properties in this population by a systematic review; Esculier et al., Disabil Rehabil 2013;35(26):2181-90) will be used to assess the severity of symptoms and functional limitations during the activities of daily living because of knee impairment. Changes in scores to this questionnaire will allow to compare the efficacy of rehabilitation protocols.
次要结局
- Changes in ankle, knee, hip and pelvis kinematics during the stance phase of running(Baseline and after the intervention (8 weeks))
- Changes in lower limb muscle strength(Baseline and after the intervention (8 weeks))
- Global rating of change (GRC)(After the intervention (8 weeks))
- Changes in pain scores using Visual analog scales (VAS)(After 4 weeks and 8 weeks of rehabilitation; 3 months after the end of the rehabilitation program)
- Changes in patellofemoral joint load during the stance phase of running(Baseline and after the intervention (8 weeks))
- Changes in the vertical loading rate of ground reaction forces during treadmill running(Baseline and after the intervention (8 weeks))