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Clinical Trials/ISRCTN97344827
ISRCTN97344827
Completed
未知

A randomised trial to evaluate early high dose therapy and autologous bone marrow transplantation as part of planned initial therapy for poor risk intermediate/high grade non-Hodgkin's lymphoma

Cancer Research UK (CRUK) (UK)0 sites0 target enrollmentJuly 1, 2001
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Conditionsymphoma (non-Hodgkin's)CancerLymphoma (non-Hodgkin's)

Overview

Phase
未知
Intervention
Not specified
Conditions
ymphoma (non-Hodgkin's)
Sponsor
Cancer Research UK (CRUK) (UK)
Status
Completed
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

  1. 2010 results in https://doi.org/10.1111/j.1365-2141.2010.08081.x (added 25/01/2019)
Registry
who.int
Start Date
July 1, 2001
End Date
October 31, 2001
Last Updated
7 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Cancer Research UK (CRUK) (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 16\-65 years
  • •2\. No medical conditions other than lymphoma, prohibiting intensive therapy. No systemic treatment for cancer in the previous 5 years
  • •3\. Histology: Follicular large cell lymphoma; Diffuse mixed cell lymphoma; Diffuse large cell lymphoma; Diffuse immunoblastic lymphoma
  • •4\. Full clinical staging to include Computed Tomography (CT) scanning of abdomen and bone marrow trephine biopsy
  • •5\. Poor prognostic features, defined as the presence of two or three of: Stage III or IV; Lactic dehydrogenase (LDH) \> normal; Performance status 2\-4 (Eastern Cooperative Oncology Group \[ECOG]\-World Health Organisation \[WHO])

Exclusion Criteria

  • •Not provided at time of registration

Outcomes

Primary Outcomes

Not specified

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