Histopathological and bacteriological study of medication-related osteonecrosis of the jaw using surgical specime
Not Applicable
- Conditions
- Medication-related Osteonecrosis of the Jaws
- Registration Number
- JPRN-UMIN000040791
- Lead Sponsor
- agasaki University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
Patients dose not have a bone sample available for the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.preoperative imaging 2.histopathology of surgical specimen 3.bacteriology of surgical specimen 4.change in morphology and number of osteoclasts on surgical specimen 5.sort, administration duratio and drug holiday of antiresorptive agent 6.postoperative imaging 7.treatment results (curing) of MRONJ 8.each collected item age, sex, primary disease, diabetes, steroid, chemotherapy, leukocytes, lymphocyte, albumin, creatinine, site, stage, trigger, treatment
- Secondary Outcome Measures
Name Time Method