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Can Alternate Day Fasting Help Reverse Liver Disease? Insights from the FAST Trial

Phase 3
Conditions
Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified
Registration Number
CTRI/2024/06/069119
Lead Sponsor
Intitute of Liver and BIliary Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

NASH patients, Age 18-65 years. BMI 25-40kg/m3, and CAP more than 290. Stable weight in the last 3 months prior to enrolling in the study(less than 5kg weight variation). Imaging showed steatotic liver disease, liver stiffness less than 14kPa measured by fibroscan. Histologically proven NASH/MASH, fibrosis up to F3. Subjects willing to participate in the study

Exclusion Criteria

Liver stiffness more than 14kPa measured by fibroscan or Fibrosis more than F3. Diabetes with HbA1c more than 8.5%. Patients with another co-existing active liver disease e.g. hepatitis B or C, alcoholic liver disease. Patients with cirrhosis, HCC, or other malignancy. Chronic kidney disease, cardiovascular disorders, uncontrolled hypertension. Chronic infections, chronic inflammatory diseases. Patients on weight loss medications e.g semaglutide. Pregnant or lactating women and those planning a pregnancy. A patient who is not willing to participate in the study, or failed to provide the consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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