Analyzing the effects of short-term fasting on transcriptome and epigenome signatures compared with food consumption in healthy subjects

Not Applicable

• Conditions: Short-term fasting; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN12651780
• Lead Sponsor: niversity of Valencia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-12-09
• Last Update Posted: 14 November 2022
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

Current inclusion criteria as of 25/07/2022:
1. White European subjects (men and women) recruited from the Mediterranean population
2. Age ranging from 18 to 50 years old
3. BMI between 21 and 34 kg/m²
_____

Previous inclusion criteria:
1. White European subjects (men and women) recruited from the Mediterranean population
2. Age ranging from 18 to 50 years old
3. BMI between 23 and 33 kg/m²

Exclusion Criteria

1. Diabetic subjects
2. Other chronic diseases (cardiovascular, cancer, respiratory diseases, liver diseases, kidney diseases, etc)
3. Subjects with food allergies or food intolerances
4. Alcohol abuse or addiction
5. Immunodeficiency, HIV-positive status, COVID-19 positive status or other acute infections
6. Serious psychiatric disorders: schizophrenia, bipolar disease, eating disorders, depression, etc
7. Any severe co-morbid condition
8. History of major organ transplantation
9. Concurrent therapy with immunosuppressive drugs or cytotoxic agents
10. Current treatment with systemic corticosteroids
11. Current use of weight loss medication
12. Any other condition that may interfere with the completion of the study protocol

Study & Design

• Study Type: Interventional
• Study Design: Not specified