A Split-face Comparative study on efficacy of Fractional CO2 Laser with PRP vs. Microneedling with PRP in Treatment of Atrophic Acne Scars
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To assess which modality is more efficacious in the treatment of Atrophic Acne scars i.e. Fractional CO2 laser with PRP or Microneedling with PRP
研究概览
简要总结
This study is done to compare the efficacy of Fractional CO2 laser with PRP versus Microneedling with PRP for treatment of atrophic acne scars along with efficacy of the individual intervention as separate entity and their adverse effects.
Acne scar treatment remains one of the greatest challenges that dermatologists face on daily basis. Fractional CO2 laser and Dermaroller has shown good results with minimal complication. PRP modality in Acne scars treatment is an emerging area and has shown good results both independently and as an adjunct with other modalities. There is paucity of study comparing Fractional CO2 laser and Microneedling with PRP as adjunct. Therefore this study has compared the efficacy of fractional CO2 laser with PRP versus Microneedling with PRP for treatment of acne scars.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •(i) Patients above the age of 18 years.
- •(ii) Patients with acne scars with > 2 points on Goodman and baron’s quantitative global acne scarring grading system over both side of face.
- •(iii) Patients who are willing to undergo the evaluation system and able to comply with all follow-up requirements.
排除标准
- •(i) Patients with active acne or any local site infection.
- •(ii) Patients with acne scars with ≤ 2 points on Goodman and baron’s quantitative global acne scarring grading system over any side of face.
- •(iii) Patients below 18years and above 60 years (iv) Patients not willing for the procedure.
- •(v) Patients having keloid or keloidal tendency (vi) Patients who have taken isotretinoin within 06 months or have undergone laser treatment or Microneedling over face within previous 01 year.
- •(vii) Any serious medical condition including bleeding diathesis, platelet disorders or in immunocompromised state.
- •(viii) Patients with past history of herpes infection.
- •(ix) Pregnant and lactating mothers.
- •(x) Patients with unrealistic expectations.
结局指标
主要结局
To assess which modality is more efficacious in the treatment of Atrophic Acne scars i.e. Fractional CO2 laser with PRP or Microneedling with PRP
时间窗: After completion of study i.e. one and half years
次要结局
- a) To asses the effectiveness of Fractional CO2 laser with PRP for treatment of Atrophic Acne scars.(b) To asses the effectiveness of Microneedling with PRP for treatment of Atrophic Acne scars.)