Age Related Changes in Calciotropic Hormones and Their Impact on Male Osteoporosis
Completed
- Conditions
- Low Bone Density
- Registration Number
- NCT00588874
- Lead Sponsor
- Yale University
- Brief Summary
The purpose of this pilot study is to generate preliminary data regarding the skeletal effects of age-related changes in calcium and vitamin D metabolism in older men.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 24
Inclusion Criteria
- healthy men age 50 yrs and older
Exclusion Criteria
- smokers
- known history of metabolic bone disease, known history of hypogonadism or renal insufficiency.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bone density of hip and spine measured after screening evaluation
- Secondary Outcome Measures
Name Time Method calciotropic hormones, including calcium, PTH and vitamin D metabolites measured after screening evaluation
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link age-related changes in vitamin D metabolism to male osteoporosis progression?
How does NCT00588874 compare to standard-of-care treatments for low bone density in older men?
Which biomarkers correlate with skeletal outcomes in age-related calcium metabolism changes in males?
What adverse events are associated with age-related calciotropic hormone fluctuations in male osteoporosis?
Are there combination therapies involving vitamin D analogs for treating male osteoporosis post-NCT00588874?
Trial Locations
- Locations (1)
Yale Center for Clinical Investigation
🇺🇸New Haven, Connecticut, United States
Yale Center for Clinical Investigation🇺🇸New Haven, Connecticut, United States