Sensitivity of cholangioscopy directed biopsies versus brush cytology in patients with malignant bileduct stenosis

Recruiting

• Conditions: bileduct stenosis; bileduct stricture; 10018008; 10004606; 10019815

• Registration Number: NL-OMON31613
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Age >= 18 year
icterus (bilirubine >2xULN)
Cholestasis (GGT or alk fos >2xULN)
dilated bile ducts on imaging with abdominal ultrasound, CT, or MRI

Exclusion Criteria

Distal CBD stenosis
Clinical conditions that do not allow ERCP with sphincterotomy such as uncorrectable coagulopathies
High suspicion of common bile duct stones
Patients unable or not willing to give informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. The difference in sensitivity between brush cytology en cholangioscopic<br /><br>directed biopsy for detection of patients with malignant biliary stricture.<br /><br>2. Cholangioscopic aspect of stricture</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Duration of examination</p><br>