Investigating the possibility and benefit of closed-loop deep brain stimulation by detecting the voluntary movement and postural tremor on patients with tremor

Not Applicable

Suspended

• Conditions: Essential Tremor (ET) or Dystonia tremor in which tremor mainly affect voluntary movement or while maintaining postures; Nervous System Diseases; Essential tremor (ET), dystonia tremor

• Registration Number: ISRCTN56186994
• Lead Sponsor: niversity of Oxford

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-02-14
• Last Update Posted: 4 May 2020
• Study Completion: 2022-01-31

Recruitment & Eligibility

• Status: Suspended
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. Aged 25 to 80 years
2. Diagnosis of essential tremor or dystonia tremor
3. Undergoing DBS for tremor symptoms

Exclusion Criteria

1. Intracranial bleeding, confusion, CSF leak or any other complication after the first stage of surgery
2. Lack of capacity to consent (judged by the clinician taking consent as not having sufficient mental capacity to understand the study and its requirements). Anyone who, in the opinion of the clinician taking consent, is unlikely to retain sufficient mental capacity for the duration of their involvement in the study.
3. Cognitive impairment/lack of capacity to perform the experimental tasks. In cases where capacity was borderline and difficult to judge subjectively, we will additionally conduct a short (10 min) quantitative assessment of cognitive function using the Mini Mental State Exam (MMSE). Patients with a score of <20 will be excluded from the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified