The Effect of Aloe Vera gel, Violet oil and Hydroxyzine on pruritus and dry skin of hemodialysis patients

Not Applicable

Conditions: Condition 1: Uremic Pruritus. Condition 2: Uremic pruritus. Condition 3: Skin dryness. Condition 4: Dialysis. Condition 5: Chronic kidney disease.
Pruritus
Xerosis cutis
Dialysis (renal)
Chronic kidney disease (CKD)
L85.3
Z49.1

Registration Number: IRCT20200727048229N1

Lead Sponsor: Birjand University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 45

Inclusion Criteria

20 Years and older
The cause of dialysis is Chronic Renal Failure.
Patients undergoing hemodialysis for at least three months
Undergoing hemodialysis at least twice a week
history of pruritus for at least 4 weeks
The severity of Itching according to the VAS scale is =3.
The severity of Dry skin according to VAS scale is =3.
Do not use other treatments to relieve Itching and Dry skin during the study including Radiation Therapy, Acupuncture, Complementary Medicine, Topical treatments, Moisturizing.
The patient does not attend another Clinical Trial within the next two months.
The absence of Pruritic and non-Pruritic skin diseases such as Atopic Dermatitis, Chronic Liver and Biliary disease, HIV, Polycythemia, Skin Eczema, No Inflammatory Skin Lesions, the absence of known allergies (based on Expert doctor's opinion)
The absence of Pregnancy and lactation
Informed consent

Exclusion Criteria

Unwillingness to continue participation in the study for any reason
Severe side effects like an allergic reaction to the Aloe Vera gel or Violet oil in patients during the intervention
Patient leaving the dialysis center during the study period (due to death, emigration, kidney transplantation).
Using other treatments to relieve pruritus during the study including Radiation Therapy, Acupuncture, Complementary Medicine, Topical Treatments
Acute disease during the intervention
Do not perform interventions for more than one week continuously.
According to the researcher's diagnosis, the person is excluded from the study.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dimensions of Pruritus. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: 5-D itch scale.;Intensity of emotions with itching. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Researcher-made questionnaire (intensity of emotions with itching).;The consequences of itching. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Researcher-made questionnaire (The consequences of itching).;The severity of itching. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The severity of dry skin. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Visual Analogue Scale (VAS).

Secondary Outcome Measures

Name	Time	Method
Quality of life. Timepoint: at weeks 0 and 8. Method of measurement: Dermatology Life Quality Iindex (DLQI).;Satisfaction rate of each intervention. Timepoint: The day after the end of each intervention. Method of measurement: Visual Analogue Scale (VAS).