Evaluation of Alvora Gel in Inflammatory Factors in Patients with Periodontitis
Phase 4
Recruiting
- Conditions
- Periodontitis.Chronic periodontitisK05.3
- Registration Number
- IRCT20100412003690N11
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Moderate to severe ?chronic periodontitis
Age 35-50
Have at least 4 teeth with probe depth of 4 mm or more in each jaw quadrant
Consent to participate in the study
Patients candidate for non-surgical treatment
Exclusion Criteria
Allergy to aloe vera or its products
Use of tobacco
Endodontic and periodontal compound lesions
Periapical lesions
Pregnancy
Severe dental caries
Semi-impacted teeth
Orthodontic patients
Systemic diseases and systemic or topical antibiotic users 6 Months befor study
Patients with periodontal disease during the past 6 months and patients receiving periodontal treatment 6 months before study
Patients receiving NSAIDs one month before sampling
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plaque Index (PI). Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using the index (O'Leary 1972).;Gingival Index (GI). Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: According to the Loe & Sillness Index.;Probe depth (PD). Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using Williams probe 6 levels of teeth.;IL-1B. Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using ELISA kit.;IL-17. Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using ELISA kit.
- Secondary Outcome Measures
Name Time Method