To assess whether pregabalin and amitriptyline can modify postoperative pain when given before surgery
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/11/038199
- Lead Sponsor
- Dr Anitha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.American Society of Anaesthesiologists physical status 1 and 2
2.Patients posted for elective inguinal hernioplasty surgery
Exclusion Criteria
1.Patient refusal
2.Known sensitivity to Pregabalin and Amitriptyline
3.History of seizure disorder
4.Known psychiatric disorder
5.History of chronic pain and chronic daily intake of analgesic
6.Liver or renal disease
7.History of drug or alcohol abuse
8.Pregnancy and breastfeeding mothers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effectiveness of pregabalin and amitriptyline in the prevention of postoperative painTimepoint: 24 hours post surgery
- Secondary Outcome Measures
Name Time Method Side effects of pregabalin and amitriptylineTimepoint: 24 hours post surgery;To measure intensity of acute postoperative painTimepoint: 24 hours post surgery;Use of rescue analgesicsTimepoint: 24 hours post surgery