Skip to main content
Clinical Trials/NCT03375684
NCT03375684
Completed
Not Applicable

Effects of Inspiratory Muscle Training on Postural Stability, Balance, Pulmonary Function and Functional Capacity in Children With Cystic Fibrosis

Bezmialem Vakif University1 site in 1 country32 target enrollmentJanuary 2, 2018
ConditionsCystic Fibrosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cystic Fibrosis
Sponsor
Bezmialem Vakif University
Enrollment
32
Locations
1
Primary Endpoint
Change from baseline limits of stability test score in Biodex Balance System SD at 8 weeks
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

It is extensively reported in the literature that patients with chronic obstructive lung disease may have impairments in balance and postural control which further increase the disease burden. Mechanisms related to these impairments include, but are not limited to increased work of breathing, diaphragm weakness, peripheral muscle weakness and systemic inflammation. Since the similar symptoms are reported for the children with cystic fibrosis, it is hypothesized that balance and postural control may also be compromised in these patients. Inspiratory muscle training (IMT) is shown to improve diaphragm strength and pulmonary function. Considering the relation between diaphragm which is one of the core muscles, and balance, IMT may also have an impact on postural control and balance alongside the standard clinical parameters such as respiratory muscle strength, pulmonary function and functional capacity in these patients. Thus, the aim of this study was to investigate the effects of inspiratory muscle training and conventional chest physiotherapy on postural stability, balance, pulmonary function and functional capacity in children with cystic fibrosis.

Registry
clinicaltrials.gov
Start Date
January 2, 2018
End Date
May 21, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Melih Zeren

Lecturer, MSc, PT

Bezmialem Vakif University

Eligibility Criteria

Inclusion Criteria

  • Cystic fibrosis diagnosis
  • Stable clinical condition (no exacerbation in last 4 weeks)

Exclusion Criteria

  • Documented diagnosis of vestibular, neurological or orthopedic disorders which may affect balance and mobility
  • Subjects previously involved in exercise training or physiotherapy programs

Outcomes

Primary Outcomes

Change from baseline limits of stability test score in Biodex Balance System SD at 8 weeks

Time Frame: Eight weeks

Change from baseline sensory integriation and balance test score in Biodex Balance System SD at 8 weeks

Time Frame: Eight weeks

Change from baseline distance covered in six-minute walk test at 8 weeks

Time Frame: Eight weeks

Change from baseline Forced Expiratory Volume in 1 second (FEV1) at 8 weeks

Time Frame: Eight weeks

Change from baseline maximum inspiratory pressure at 8 weeks

Time Frame: Eight weeks

Change from baseline postural stability test score in Biodex Balance System SD at 8 weeks

Time Frame: Eight weeks

Change from baseline Forced Vital Capacity (FVC) at 8 weeks

Time Frame: Eight weeks

Change from baseline Peak Expiratory Flow (PEF) at 8 weeks

Time Frame: Eight weeks

Change from baseline maximum expiratory pressure at 8 weeks

Time Frame: Eight weeks

Secondary Outcomes

  • Change from baseline m. quadriceps strength at 8 weeks(Eight weeks)

Study Sites (1)

Loading locations...

Similar Trials