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Effects of Inspiratory Muscle Training on Postural Stability, Balance, Pulmonary Function and Functional Capacity in Children With Cystic Fibrosis

Not Applicable
Completed
Conditions
Cystic Fibrosis
Interventions
Other: Conventional chest physiotherapy
Other: Inspiratory muscle training
Registration Number
NCT03375684
Lead Sponsor
Bezmialem Vakif University
Brief Summary

It is extensively reported in the literature that patients with chronic obstructive lung disease may have impairments in balance and postural control which further increase the disease burden. Mechanisms related to these impairments include, but are not limited to increased work of breathing, diaphragm weakness, peripheral muscle weakness and systemic inflammation. Since the similar symptoms are reported for the children with cystic fibrosis, it is hypothesized that balance and postural control may also be compromised in these patients. Inspiratory muscle training (IMT) is shown to improve diaphragm strength and pulmonary function. Considering the relation between diaphragm which is one of the core muscles, and balance, IMT may also have an impact on postural control and balance alongside the standard clinical parameters such as respiratory muscle strength, pulmonary function and functional capacity in these patients. Thus, the aim of this study was to investigate the effects of inspiratory muscle training and conventional chest physiotherapy on postural stability, balance, pulmonary function and functional capacity in children with cystic fibrosis.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
32
Inclusion Criteria
  • Cystic fibrosis diagnosis
  • Stable clinical condition (no exacerbation in last 4 weeks)
Exclusion Criteria
  • Documented diagnosis of vestibular, neurological or orthopedic disorders which may affect balance and mobility
  • Subjects previously involved in exercise training or physiotherapy programs

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Control GroupConventional chest physiotherapyPatients in this group will receive conventional chest physiotherapy, two times a day, 7 days a week for 8 weeks. One exercise session will be supervised in a clinic per week, other sessions will be performed at home.
Training GroupConventional chest physiotherapyIn addition to conventional chest physiotherapy programme, patients in this group will also receive inspiratory muscle training for 15 minutes, twice a day, 7 days a week for 8 weeks. One exercise session will be supervised in a clinic per week, other sessions will be performed at home.
Training GroupInspiratory muscle trainingIn addition to conventional chest physiotherapy programme, patients in this group will also receive inspiratory muscle training for 15 minutes, twice a day, 7 days a week for 8 weeks. One exercise session will be supervised in a clinic per week, other sessions will be performed at home.
Primary Outcome Measures
NameTimeMethod
Change from baseline limits of stability test score in Biodex Balance System SD at 8 weeksEight weeks
Change from baseline sensory integriation and balance test score in Biodex Balance System SD at 8 weeksEight weeks
Change from baseline distance covered in six-minute walk test at 8 weeksEight weeks
Change from baseline Forced Expiratory Volume in 1 second (FEV1) at 8 weeksEight weeks
Change from baseline maximum inspiratory pressure at 8 weeksEight weeks
Change from baseline postural stability test score in Biodex Balance System SD at 8 weeksEight weeks
Change from baseline Forced Vital Capacity (FVC) at 8 weeksEight weeks
Change from baseline Peak Expiratory Flow (PEF) at 8 weeksEight weeks
Change from baseline maximum expiratory pressure at 8 weeksEight weeks
Secondary Outcome Measures
NameTimeMethod
Change from baseline m. quadriceps strength at 8 weeksEight weeks

Trial Locations

Locations (1)

Bezmialem Vakif Universitesi, Department of Physiotherapy and Rehabilitation

🇹🇷

Istanbul, Eyup, Turkey

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