The Effect of Antenatal Dexamethasone to Improve Respiratory Neonatal Outcomes in Late Preterm Birth :A Randomized Controlled Trial

none0 sites194 target enrollmentNovember 8, 2020

Overview

No summary available.

Registry

who.int

Start Date

November 8, 2020

End Date

January 31, 2020

Last Updated

last year

Study Type

Interventional

Sex

Male

Sponsor

none

•Criteria for inclusion in the study were women (a) had preterm labor defined as regular uterine contractions before 37 weeks accompanied by a change of cervical dilatation, effacement, or both, or initial presentation with regular contractions and cervical dilatation at least 2 cm (16\) or (b) had spontaneous rupture of membranes (preterm PROM), diagnosed by pooling of fluid at posterior fornix with speculum examination, positive cough test and positive alkaline pH test or (c) had fetal or maternal indications for delivery between 34 and 36\+6 weeks gestation, such as placenta previa or fetal growth restriction.

•We excluded women with multiple gestations, those who had received a previous course of corticosteroids, infection or chorioamnionitis (fetal tachycardia\>160 bpm, maternal fever \> 37\.8 Â°C and foul smelling amniotic fluid) during labor, overt diabetes mellitus, gestational diabetes mellitus, cervical dilation more than 5 centimeters, thrombocytopenia, allergy to corticosteroids, preeclampsia severe feature and HELP syndrome.