Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation of Balance

Not Applicable

• Conditions: Electromyography; Electroencephalography; Balanced
• Interventions: Device: Sham stimulation; Device: electrical noise stimulation; Device: Foam

• Registration Number: NCT05570890
• Lead Sponsor: National Yang Ming Chiao Tung University

Brief Summary

Noise stimulation had an immediate effect on improving balance control. The present study aimed to clarify the immediate neuromuscular adaptation induced by noise stimulation and find the correlation between neuromuscular adaptation and functional performance.

Detailed Description

The mechanism behind noise stimulation is called Stochastic Resonance which improves the detectivity of sensory input with the presence of noise, making sub-sensory threshold input detectable. Noise stimulation had been proved to improve postural control, Ia afferent sensitivity, and muscle activity of the tibialis anterior. With this evidence of the effect of noise stimulation on balance enhancement, the neuromuscular adaptation induced by noise stimulation has not been researched yet. Therefore, the present study aims to clarify the immediate effect of noise on neuromuscular regulation during postural control.

Study Timeline

• Study Start: 2022-04-29
• Status Verified: 2022-07
• Study First Submitted: 2022-08-14
• Study First Submitted QC: 2022-10-06
• Last Update Submitted: 2022-10-06
• Study First Posted: 2022-10-07
• Last Update Posted: 2022-10-07
• Primary Completion: 2022-11-30
• Study Completion: 2023-01-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• age between 20 and 40 years old
• without ankle injury history in 1 year
• without musculoskeletal or neurological diseases that would affect balance performance
• without visual impairment (except vision correction or no visual problems)
• without vestibular impairment.

Exclusion Criteria

• subject who cannot tolerate the cutaneous electrical stimulation to induce H reflex
• single-leg stance (SLS) without support is shorter than 80 secs

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Sham stimulation on stable surface	Sham stimulation	The participant will not receive stimulation and will stand on flat ground.
Sham stimulation on unstable surface	Sham stimulation	The participant will not receive stimulation and will stand on foam.
Sham stimulation on unstable surface	Foam	The participant will not receive stimulation and will stand on foam.
Noise stimulation on stable surface	electrical noise stimulation	The participant will receive stimulation with intensity set at 90% of their sensory threshold and will stand on flat ground.
Noise stimulation on unstable surface	electrical noise stimulation	The participant will receive stimulation with intensity set at 90% of their sensory threshold and will stand on foam.
Noise stimulation on unstable surface	Foam	The participant will receive stimulation with intensity set at 90% of their sensory threshold and will stand on foam.

Primary Outcome Measures

Name	Time	Method
Mean sway velocity of the center of pressure	40 seconds under each condition	The mean sway velocity in mm/sec will represent balance performance
Co-activation index	40 seconds after each condition	Co-activation index will be calculated by EMG activity of Tibialis Anterior and Soleus muscle to represent the muscle activity.
Mean sway path of the center of pressure	40 seconds under each condition	The mean sway path in mm will represent balance performance
Cortical excitability	40 seconds under each condition	Power spectrum density of EEG will calculated for representing cortical excitability.
Spinal reflex excitability	40 seconds under each condition	H reflex amplitude will represent the excitability of peripheral control from spinal level nerve system.

Trial Locations

Locations (1)

National Yang-Ming University; 🇨🇳 Taipei, Taiwan