The Research About the ACS After Femoropopliteal Arterial Injuries
Recruiting
- Conditions
- Acute Compartment Syndrome
- Registration Number
- NCT05030259
- Lead Sponsor
- Hebei Medical University Third Hospital
- Brief Summary
Crural Compartment syndrome is a well-known sequela after femoropopliteal arterial injuries in the lower extremity, particularly when there has been a long period of ischemia,need for ligation of a major vein, or when there is severe associated soft tissue.There is conteoversy in the treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- patients with femoropopliteal arterial injuries
- patients older than 18 years
Exclusion Criteria
- Patients who did not survive to discharge
- Patients with primary amputation
- patients younger than 18 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the rate of amputation up to 6 months fasciotomy performed or not up to 2 weeks
- Secondary Outcome Measures
Name Time Method hospital lengths of stay up to 6 months injury mechanism of patients up to 1 week the costs of hospitalization up to 2 months the time of using tourniquet up to 1 week concomitant injury of patients up to 1 week admission lactate of patients up to 1 month admission International Normalized Ratio of patients up to 1 month tourniquet used or not up to 1 week the time to surgical intervention up to 1 month extremity Abbreviated Injury Scale of patients up to 1 week minimum is 1, maximum is 6, higher scores mean a worse outcome
Injury Severity Score of patients up to 1 week minimum is 0, maximum is 75, higher scores mean a worse outcome
time of skin closure up to 1 month admission hemoglobin of patients up to 1 month admission pH of patients up to 1 month postoperative lactate of patients up to 1 month postoperative International Normalized Ratio of patients up to 1 month admission CK of patients up to 1 month postoperative CK of patients up to 1 month admission LDH of patients up to 1 month postoperative LDH of patients up to 1 month Number of Participants with Lower Extremity Arteriosclerosis Obliterans up to 1 week vascular repair technique of patients up to 1 week Number of Participants with sepsis up to 1 month Ischemia time of patients up to 1 week Postoperative knee function of patients up to 6 month the rate of primary skin closure up to 1 months
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms contribute to crural compartment syndrome after femoropopliteal arterial injuries?
How does the incidence of acute compartment syndrome in NCT05030259 compare to standard-of-care outcomes for lower extremity vascular trauma?
Are there specific biomarkers that identify patients at higher risk for developing ACS following femoropopliteal artery ligation?
What are the most effective management strategies for preventing or treating adverse events in ACS following arterial injury?
What combination therapies or alternative approaches are being explored as competitors to observational treatment protocols for femoropopliteal arterial injury-induced compartment syndrome?
Trial Locations
- Locations (1)
the Third Hospital of Hebei Medical Univesity
🇨🇳Shijiazhuang, Hebei, China
the Third Hospital of Hebei Medical Univesity🇨🇳Shijiazhuang, Hebei, ChinaSun ChangshengContact1517613931015176139310@163.com