Blue Sky Study: Impact of Milk and Vitamin D for Child Growth and Health
Phase 2
Completed
- Conditions
- Vitamin d Deficiency
- Interventions
- Dietary Supplement: Milk SubstituteDietary Supplement: Seasonal D supplementDietary Supplement: Mongolian milk without vitamin DDietary Supplement: Mongolian milk with vitamin DDietary Supplement: Daily D supplementDietary Supplement: UHT milk
- Registration Number
- NCT00886379
- Lead Sponsor
- Brigham and Women's Hospital
- Brief Summary
This intervention study will address the impact of vitamin D fortified milk and vitamin D supplements on the growth, levels of vitamin D, insulin-like growth factor 1, growth hormone, academic attention, respiratory infections, asthma, and flexural dermatitis (a proxy for eczema) of Mongolian children.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 597
Inclusion Criteria
-
Children in 3rd and 4th grade from selected Mongolian schools.
-
School selection will consider:
- socioeconomic position;
- geographic location;
- school size;
- current lunch or supplementation program; and
- the interest and willingness to participate of the school's administration and faculty.
Exclusion Criteria
- Allergy to milk or wheat products.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 4 Milk Substitute Milk Substitute 5 Seasonal D supplement Seasonal D 1 Mongolian milk without vitamin D Mongolian milk without D 2 Mongolian milk with vitamin D Mongolian milk with vitamin D 6 Daily D supplement Daily D 3 UHT milk Ultra High Temperature (UHT) milk
- Primary Outcome Measures
Name Time Method Serum 25-hydroxyvitamin D Concentrations in Schoolchildren Blood was analyzed at day 0 and day 49 Baseline and Follow-up 25(OH)D3 by liquid chromatography-tandem mass spectrometry
- Secondary Outcome Measures
Name Time Method