How Avatar Can Enhance Autobiographical Memory of Patients With Substance Use Disorder

Not Applicable

Completed

• Conditions: Substance Use Disorder (SUD)

• Registration Number: NCT06806943
• Lead Sponsor: Le.L.A.T. Lega Lotta Aids E Tossicodipendenza

Brief Summary

The goal of this study is to investigate whether the use of artificial intelligence platforms can promote the retrieval of specific positive autobiographical memories.

Detailed Description

The decision to focus on the retrieval of positive autobiographical memories was made for ethical reasons and is not tied to any specific research hypothesis. Specifically, the study aims to assess whether artificial intelligence facilitates the sharing of personal experiences and reflection on autobiographical memories related to substance use disorders, taking into account the potential influence of individual characteristics such as recent mood state, and overall memory functioning.

Study Timeline

• Study Start: 2024-07-01
• Primary Completion: 2024-12-15
• Study Completion: 2024-12-15
• Status Verified: 2025-01
• Study First Submitted: 2025-01-27
• Study First Submitted QC: 2025-01-30
• Last Update Submitted: 2025-01-30
• Study First Posted: 2025-02-04
• Last Update Posted: 2025-02-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 42

Inclusion Criteria

• Clinical diagnosis of substance use disorder
• Admitted to the drug rehabilitation center for at least 3 months
• Aged 18 years or older

Exclusion Criteria

• Previous neurological pathologies
• Previous cognitive deficits

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change in Specific Autobiographical Memory Recall	During the intervention sessions for both conditions (avatar-based and face-to-face). This outcome directly reflects the study's objective by quantifying the change of AM recall through avatar-based interventions.	The primary outcome measure is the difference in the number of specific autobiographical memories recalled between the avatar-based interaction condition and the face-to-face condition, as assessed by the Autobiographical Memory Test (AMT). Specificity of recalled memories are scored using standardized criteria. This measure evaluates the effectiveness of avatar-based interventions in changing AM recall in patients with substance use disorder (SUD).

Secondary Outcome Measures

Name	Time	Method
Latency of Autobiographical Memory Recall	During the intervention sessions for both conditions (avatar-based and face-to-face).	The secondary outcome measure is the comparison of latency times (time taken to recall a memory) between the avatar-based interaction condition and the face-to-face condition, as recorded during the Autobiographical Memory Test (AMT). This measure evaluates whether the use of avatar-based interventions change the speed of autobiographical memory recall in patients with substance use disorder (SUD).
Pleasantness of Autobiographical Memories Recalled	During the intervention sessions for both conditions (avatar-based and face-to-face).	The secondary outcome measure is the comparison of pleasantness ratings of autobiographical memories recalled between the avatar-based interaction condition and the face-to-face condition. Pleasantness is assessed during the Autobiographical Memory Test (AMT). This measure evaluates whether avatar-based interventions change the emotional valence of the memories retrieved by patients with substance use disorder (SUD).
Change in Age Memory Recall	During the intervention sessions for both conditions (avatar-based and face-to-face).	The secondary outcome measure is the change in age memory recall, defined as the participants' ability to identify the age at which autobiographical memories occurred, comparing the avatar-based interaction condition to the face-to-face condition. Age memory is assessed during the Autobiographical Memory Test (AMT) for each recalled memory. This measure evaluates whether avatar-based interventions change temporal specificity in autobiographical memory recall among patients with substance use disorder (SUD).

Trial Locations

Locations (1)

Le.L.A.T. Lega Lotta Aids E Tossicodipendenza; 🇮🇹 Messina, Italy