Glucose as a Mediator of Self-control Performances in Patients With Schizophrenia: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Blood Glucose Level
研究概览
简要总结
The research aims to investigate the relationship between self-control ability and blood glucose level in schizophrenic patients. The main purpose of the present study is to explore whether the close relationship of blood glucose and self-regulatory strength observed in healthy individuals, is applicable to schizophrenic patients. More specifically, the current study aims
- to investigate whether the exertion of self-control reduces blood glucose,
- to examine whether low level of blood glucose deteriorates subsequent self-control performances
- to examine whether restoring the glucose level eliminates these impairments, in schizophrenic patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 15 or above
- •DSM-IV diagnosis of schizophrenia, schizoaffective disorder, schizophreniform psychosis, brief psychosis, psychosis NOS or delusional disorder
- •Cantonese-speaking Chinese
- •Ability to understand the nature of the study and sign informed consent
排除标准
- •Organic Brain disorder
- •Known history of intellectual disability
- •Priority Follow Up (Subtarget or Target)
- •All allergic to any sugar or artificial sweeteners
- •Diabetics
- •Physical Disability
研究组 & 干预措施
Glucose & Depleting
participants will perform in a depleting task and receive a glucose drink
干预措施: glucose drink (Dietary Supplement)
Glucose & non-depleting
participants will perform in a non-depleting task and receive a glucose drink
干预措施: glucose drink (Dietary Supplement)
Placebo & depleting
participants will perform in a depleting task and receive a placebo drink
Placebo & non depleting
participants will perform in a non depleting task and receive a placebo drink
结局指标
主要结局
Blood Glucose Level
时间窗: baseline, after depleting task
self control tasks (handgrip, stroop, figure tracing task)
时间窗: after 12-minutes metabolizing phase
次要结局
未报告次要终点