Glucose as a Mediator of Self-control Performances in Patients With Schizophrenia

Not Applicable

• Conditions: Schizophrenia
• Interventions: Dietary Supplement: glucose drink

• Registration Number: NCT01563016
• Lead Sponsor: The University of Hong Kong

Brief Summary

The research aims to investigate the relationship between self-control ability and blood glucose level in schizophrenic patients. The main purpose of the present study is to explore whether the close relationship of blood glucose and self-regulatory strength observed in healthy individuals, is applicable to schizophrenic patients. More specifically, the current study aims

* to investigate whether the exertion of self-control reduces blood glucose,

* to examine whether low level of blood glucose deteriorates subsequent self-control performances

* to examine whether restoring the glucose level eliminates these impairments, in schizophrenic patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-03
• Study First Submitted: 2012-03-22
• Study First Submitted QC: 2012-03-23
• Last Update Submitted: 2012-03-23
• Study First Posted: 2012-03-26
• Last Update Posted: 2012-03-26
• Study Start: 2012-04
• Primary Completion: 2013-04
• Study Completion: 2013-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Aged 15 or above
• DSM-IV diagnosis of schizophrenia, schizoaffective disorder, schizophreniform psychosis, brief psychosis, psychosis NOS or delusional disorder
• Cantonese-speaking Chinese
• Ability to understand the nature of the study and sign informed consent

Exclusion Criteria

• Organic Brain disorder
• Known history of intellectual disability
• Priority Follow Up (Subtarget or Target)
• All allergic to any sugar or artificial sweeteners
• Diabetics
• Physical Disability

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Glucose & Depleting	glucose drink	participants will perform in a depleting task and receive a glucose drink
Glucose & non-depleting	glucose drink	participants will perform in a non-depleting task and receive a glucose drink

Primary Outcome Measures

Name	Time	Method
Blood Glucose Level	baseline, after depleting task
self control tasks (handgrip, stroop, figure tracing task)	after 12-minutes metabolizing phase

Trial Locations

Locations (1)

The University of Hong Kong; 🇨🇳 Hong Kong, China