To compare carbetocin and oxytocin for blood pressure changes in pregnant women under going lscs
Phase 4
- Conditions
- Health Condition 1: 1- Obstetrics
- Registration Number
- CTRI/2023/04/051782
- Lead Sponsor
- ABVIMS and Dr RML Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Uncomplicated Term Pregnant Women with singleton pregnancy scheduled for elective caesarean section under spinal anaesthesia
Exclusion Criteria
Pregnant Women with American Society of Anaesthesiologists physical status III and above.
Women having conditions with increased risk of uterine atony and PPH such as, pre eclampsia, eclampsia, multiple gestation, placenta previa, uterine fibroids and previous history of uterine atony and PPH.
Females with a history of bleeding diasthesis or thromboembolic diseases.
Women who are a known case of chronic medical diseases(renal, hepatic or cardiovascular diseases)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of change in mean arterial pressure after administration of the study drugsTimepoint: Time of skin incision(T0) <br/ ><br>1 Minute(T1) <br/ ><br>3 Minutes(T3) <br/ ><br>5 Minutes(T5) <br/ ><br>10 Minutes(T10)
- Secondary Outcome Measures
Name Time Method Averse effects of the two drugs, if anyTimepoint: Every five minutes from the time of administration of the drug till the end of the surgery;Changes in heart rate after administration of study drugsTimepoint: Time of skin incision(T0) <br/ ><br>1 Minute(T1) <br/ ><br>3 Minutes(T3) <br/ ><br>5 Minutes(T5) <br/ ><br>10 Minutes(T10);Need for use of additional uterotonicsTimepoint: In first 24 hours after surgery;Uterine tone after administration of study drugsTimepoint: 3 Minutes(T3) <br/ ><br>5 Minutes(T5) <br/ ><br>10 Minutes(T10)