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Clinical Trials/NCT05269095
NCT05269095
Unknown
Not Applicable

Analgesic Effect of Adductor Canal Block Combined With Infiltration of the Interspace Between Popliteal Artery and the Capsule of the Knee (IPACK) Block Versus Genicular Nerves Block in Knee Arthroscopy

Tanta University0 sites105 target enrollmentMarch 21, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Arthroscopy
Sponsor
Tanta University
Enrollment
105
Primary Endpoint
Postoperative 24-hour rescue analgesic consumption
Last Updated
4 years ago

Overview

Brief Summary

This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of posterior knee (IPACK) block compared to genicular nerves block in patients undergoing knee arthroscopy.

Detailed Description

Maintaining patient safety, ensuring best patient outcomes, and optimal pain relief post-operatively are of utmost concern for anesthesia providers. Adequate pain relief attenuates stress responses and long-term chronic pain complications while contributing to improved postoperative outcomes. Knee arthroscopy is a very common procedure and very often is performed as day-case surgery. Ambulatory arthroscopic surgery of the knee is preferred by the majority of properly selected and well-informed patients. It has been reported that a significant number of patients have moderate to severe pain 24 hours after ambulatory surgery in general and knee arthroscopy in particular and pain affects the patient's activity level and satisfaction. Adductor canal block (ACB) is a popular peripheral nerve block that has been shown to decrease the pain significantly and decrease opioid consumption with minimal effect on quadriceps function. It provides analgesia to the peri-articular and intra-articular aspects of the knee joint but doesn't relieve posterior knee pain which is moderate to severe in intensity.

Registry
clinicaltrials.gov
Start Date
March 21, 2022
End Date
March 21, 2023
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Muhammad Ahmed Kandil

Resident of Anesthesiology and Surgical Intensive Care and Pain Medicine

Tanta University

Eligibility Criteria

Inclusion Criteria

  • Age 21-60 years
  • Both genders
  • American Society of Anaesthesiologists physical status classification I - III
  • Patients scheduled for elective unilateral knee arthroscopy under spinal anesthesia

Exclusion Criteria

  • Patient refusal
  • Preoperative neurological deficits
  • Opioid-dependent (opioid intake more than 3 months)
  • Chronic pain conditions
  • Significant cardiac and respiratory disease
  • Pre-existing major organ dysfunction such as hepatic and renal failure
  • Coexisting hematological disorder or deranged coagulation parameters
  • Psychiatric illnesses
  • Allergy to any of the drugs used in the study

Outcomes

Primary Outcomes

Postoperative 24-hour rescue analgesic consumption

Time Frame: 24 hours postoperative

Total postoperative 24-hour rescue analgesic consumption will be recorded

Secondary Outcomes

  • Post-operative pain(24 hours Postoperative)
  • Time taken till 1st rescue analgesic request(24 hours Postoperative)

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