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Clinical Trials/NCT04986878
NCT04986878
Completed
Not Applicable

Comparison Between the Analgesic Effects of Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty

Aswan University Hospital2 sites in 1 country60 target enrollmentMarch 15, 2017
ConditionsRheumatism Knee

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rheumatism Knee
Sponsor
Aswan University Hospital
Enrollment
60
Locations
2
Primary Endpoint
postoperative pain scores by visual analogue score
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Adductor canal block (ACB) has emerged as an option for postoperative regional analgesia in patients undergoing total knee arthroplasty (TKA).

Detailed Description

Various approaches to the performance of peripheral nerve blocks for postoperative pain control in patients undergoing TKA have been described in the literature. These approaches include lumbar plexus block, femoral nerve block (FNB), with or without a sciatic nerve block, and most recently the ACB. FNB is a commonly used modality for postoperative analgesia after TKA. It is considered by some as the gold standard or the cornerstone of postoperative analgesia after TKA. However, FNB reduces quadriceps muscle strength essential for mobilization and active contribution in any physical rehabilitation program. Quadriceps weakness places the patients at risk of falling. which may be detrimental to postoperative recovery. The ACB has recently emerged as an appealing alternative to FNB as it is predominately a sensory nerve block of a more distal branch of the femoral nerve ( the saphenous nerve).

Registry
clinicaltrials.gov
Start Date
March 15, 2017
End Date
June 30, 2018
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Aswan University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Huda Fahmy Mahmoud, PhD

Assistant professor of Anesthesia and Intensive Care

Aswan University Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients scheduled for primary total knee arthroplasty with
  • American Society of Anesthesiologists (ASA) physical status I -III,
  • mentally competent and able to give consent for enrollment in the study.

Exclusion Criteria

  • Patient younger than 18 years old or older than 70 years old
  • Allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone, and any of the drugs included in the multimodal perioperative pain protocol.
  • Revision surgeries were excluded.
  • Impaired kidney functions and patients with coagulopathy were also excluded.
  • Chronic pain syndromes and patients with chronic opioid use defined as the use of regular daily doses of systemic narcotics for the past 6 months prior to the surgery.
  • BMI of 40 or more
  • Pregnancy (positive urine pregnancy test result in Preop area on the morning of surgery)

Outcomes

Primary Outcomes

postoperative pain scores by visual analogue score

Time Frame: 48 hours

visual analogue score is a straight, vertical 10-cm line with the bottom point representing "no pain" = (0cm) and the top point representing "the worst pain you could ever have" = (10 cm).

Secondary Outcomes

  • the 30-Second Chair test(48 hours)
  • six-minute walking test(48 hours)
  • time to up and go test (minutes)(48 hours)

Study Sites (2)

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