Anterior Temporal Epilepsy Neuropsychological Assessment of Faces

Not Applicable

• Conditions: Anterior Temporal Lobectomy; Anterior Temporal Epilepsy; Face Perception

• Registration Number: NCT02888925
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

The purpose is to evaluate neuropsychological effects of anterior temporal epilepsy in face perception by comparison of performances of epileptic patients and control individuals, sex-, age- and socio-educational level-matched.

Secondary purposes are to prospectively evaluate neuropsychological impact of anterior temporal lobectomy performed for surgical treatment of anterior temporal epilepsy on face perception (exploratory study).

Detailed Description

Not available

Study Timeline

• Study Start: 2013-08
• Study First Submitted: 2016-08-31
• Study First Submitted QC: 2016-08-31
• Study First Posted: 2016-09-05
• Primary Completion: 2017-09
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-23
• Last Update Posted: 2019-07-24
• Study Completion: 2020-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

ALL:

• Informed consent
• Affiliation to social security
• Preliminary medical examination

PATIENTS WITH EPILEPSY:

• Symptomatic drug-resistant anterior temporal epilepsy (confirmed with video-electroencephalography and magnetic resonance imaging and if necessary intracerebral SEEG exploration)
• Patient needing anterior temporal lobectomy and undergoing pre-surgery conventional intercritical assessment for surgery decision
• Nonverbal IQ ≥ 70 (WAIS-IV)
• At least 6 successful VOSP tests (perception test)

Exclusion Criteria

ALL:

• persons under legal protection or incapable to consent
• Persons deprived of liberty by juridical or administrative decision

PATIENTS WITH EPILEPSY:

• Sever visual disorders of neurological or ophthalmological origin

CONTROL INDIVIDUALS:

• Psychiatric or neurological disorders
• Important ophthalmological disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Scores obtained with Benton test by patients with anterior temporal epilepsy and matched control individuals	day 0

Secondary Outcome Measures

Name	Time	Method
Change of scores obtained with Benton test by epilepsy patients before and after lobectomy and control individuals (only patients having undergone anterior temporal lobectomy and matched control individuals)	day 0 and after 24 to 30 months

Trial Locations

Locations (1)

Service de Neurologie, Hôpital Central, CHU de Nancy; 🇫🇷 Nancy, France