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Clinical Trials/DRKS00004573
DRKS00004573
Recruiting
Not Applicable

Predictors of outcome in heart failure with preserved ejection fraction - HFPEF

Medizinische Universität Wien, Allgemeines Krankenhaus der Stadt Wien, Universitätsklinik II für Innere Medizin , Abteilung für Kardiologie0 sites350 target enrollmentDecember 12, 2012
ConditionsI50.19I27.28

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
I50.19
Sponsor
Medizinische Universität Wien, Allgemeines Krankenhaus der Stadt Wien, Universitätsklinik II für Innere Medizin , Abteilung für Kardiologie
Enrollment
350
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 12, 2012
End Date
TBD
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Medizinische Universität Wien, Allgemeines Krankenhaus der Stadt Wien, Universitätsklinik II für Innere Medizin , Abteilung für Kardiologie

Eligibility Criteria

Inclusion Criteria

  • Inclusion Criteria:
  • 1\. Age \= 18 years
  • 2\. written informed consent
  • 3\. symptoms or signs of heart failure (NYHA \> I)
  • 4\. transthoracic echocardiography:
  • LVEF \> 50 %
  • LVEDVI \< 97ml/m2
  • E/E' \> 15
  • 15\>E/e’\>8 and NT\-proBNP \> 220pg/ml
  • 5\. Right heart catheter

Exclusion Criteria

  • Exclusion Criteria:
  • 1\. Inability or unwillingness to perform any of the diagnostic tests and to participate in follow\-up visits
  • 2\. Left ventricular ejection fraction \=50%
  • 3\. Significant valvular heart disease
  • 4\. Congenital heart disease
  • 5\. Significant coronary artery disease requiring percutaneous coronary intervention or aorto\-coronary bypass surgery
  • 6\. Left ventricular diastolic dysfunction without symptoms or signs of heart failure, such as presence or history of dyspnea at rest, fluid retention, jugular vein distension
  • 7\. Severe chronic renal insufficiency (GFR \<30 ml/min)
  • 8\. Pregnancy
  • 9\. Bronchial asthma or COPD with Forced Expiratory Volume in one second (FEV1\) \<60% predicted

Outcomes

Primary Outcomes

Not specified

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