The efficacy of pilocarpine for xerostomia induced by radiation therapy at different administration timing.
Not Applicable
Not yet recruiting
- Conditions
- xerostomia
- Registration Number
- JPRN-UMIN000010288
- Lead Sponsor
- Kawasaki Medical School
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients who have contraindication to pilocarpine. 2. Pregnant women or patients who have possibility of pregnancy. 3. Patients the principal investigator deems unsuitable as a subject.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method a visual analog scale xerostomia questionnaire quantity of secreted saliva
- Secondary Outcome Measures
Name Time Method Oral findings
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie pilocarpine's efficacy in treating radiation-induced xerostomia?
How does pilocarpine compare to standard-of-care saliva substitutes in managing xerostomia post-radiation therapy?
Are there specific biomarkers that predict response to pilocarpine in patients with radiation-induced salivary gland dysfunction?
What are the potential adverse events associated with pilocarpine administration timing in xerostomia treatment?
What combination therapies or alternative cholinergic agonists show promise for radiation-induced xerostomia management?