TCTR20221130004已完成3 期
Efficacy of As-Needed Pilocarpine for the Treatment of Radiation-Induced Xerostomia: A Double-Blind, Randomized, Placebo-Controlled, Crossover Study
Ratchadapisek Pageant Research Fund0 个研究点目标入组 20 人开始时间: 2022年11月30日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1. Age 18 years old and above
- •2. Diagnosed with head and neck cancer
- •3. Underwent radiotherapy (IMRT or 3D-CRT technique) more than 6 months prior to entering this study
- •4. History of xerostomia
- •5. Clinical Oral Dryness Score 3 and above
- •6. Can understand Thai
- •7. Able to attend follow-up visits
- •8. Consent to be in the study
排除标准
- •1. Pilocarpine allergy
- •2.Autoimmune disease
- •3.Patient with current medications affecting salivary flows
- •4. Patient with swallowing proble or currently using nasogastric tube feeding
- •5.Patient with current use of pilocarpine or other sialogogue within 1 month prior to the study
- •6. Pregnant woman and lactating woman
- •7. Patient underwent oral surgery and salivary gland surgery
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