Vitamin D suppletion and aspecific musculo-skeletal disorders

Phase 4

Completed

• Conditions: 10028302; musculo-skeletal disorders; widespread pain

• Registration Number: NL-OMON33615
• Lead Sponsor: F. Schreuder

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 82

Inclusion Criteria

asian or african origin
18-60 yrs
> 6wk complaininig of muscle-pain or weakness

Exclusion Criteria

Specific diseases causing musclepain like polymyalgia rheumatica, arthritis (depression or fibromyalgia or somatisationdisorder are no exclusion-criteria)
use of statines or ciclosporine
use of vit D suppletion in the past 4 months
ESR > 30, Kreat > 150 mmol/L
sarcoidose, TBC

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>difference in complaints between inclusion date and 6 weeks after 150.000 IU<br /><br>cholecalciferol or 300.000 IU</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>difference in complaints between inclusion date and 12 weeks after 150.000 IU<br /><br>cholecalciferol (or placebo)<br /><br><br /><br>difference in improvement in localisation of complaints<br /><br>vit D level on inclusion<br /><br>vit D level at 12 weeks<br /><br>difference in vit D levels wee12 and on inclusion with 150.000 or 300.000 IU</p><br>