A clinical study of transcutaneous electrical acupoint stimulation combined with multi-modal analgesia in ERAS mode on improving pain and accelerating functional recovery after TKA
- Conditions
- knee osteoarthritis
- Registration Number
- ITMCTR2200006633
- Lead Sponsor
- Wangjing Hospital of China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) Meet the diagnostic criteria of western medicine and traditional Chinese medicine for knee osteoarthritis, and the joint space is obviously narrowed on the weight-bearing frontal X-ray film, which is in line with Kellgren and Lawrence imaging grades III and IV, and is in line with unilateral total knee arthroplasty ( TKA) standard; patients with indications for surgery and ineffective after non-surgical treatment, patients and their families who are willing to undergo surgery.
(2) Aged 55-75 years old;
(3) The patient has normal intelligence, no language barrier, willing to receive treatment, and can cooperate with the doctor to successfully complete the postoperative pain grading score;
(4) The patient himself agrees and signs the consent form. effect, and its mechanism of effect in enhancing postoperative analgesic efficacy.
(1) Those who have a history of allergies to alcohol, morphine, non-steroidal anti-inflammatory drugs or local anesthetics;
(2) Those who have used sedatives, opioids for a long time, a history of alcohol abuse, and drug addicts;
(3) Postoperative patients Unstable vital signs, obvious high fever and chills, large fluctuations in blood pressure and heart rate;
(4) Neurosis and psychiatric patients;
(5) Postoperative prosthesis loosening, periprosthetic fracture, quadriceps tendon rupture, patellar tendon
(6) Those who are prone to bleeding and have severe heart, lung and renal insufficiency;
(7) Those who suffer from other rheumatism and metabolic diseases at the same time, such as gout, rheumatoid arthritis, Hemophilia, ankylosing spondylitis, etc;
(8) Those with electromagnetic devices in the body, such as cardiac pacemakers;
(9) Patients with purulent, non-specific knee joint infectious inflammation;
(10) At the same time Traumatic synovitis, villonodular pigmented synovitis and other patients with knee joint synovium as the main lesion.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual Analog Scale(VAS);Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC);
- Secondary Outcome Measures
Name Time Method Survival of life-12(SF-12);pain threshold;Pain Sensitization Assessment;Infrared thermal imaging;Opioid-related adverse reactions;Quadriceps motor unit potential duration and amplitude;ß-Endorphin(ß-EP);The dosage, frequency and time of use of drugs in the analgesic pump;