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Clinical Trials/NCT06099977
NCT06099977
Recruiting
N/A

The Effect of Preoperative Binaural Sound on Remimazolam Dose Required for Induction of General Anesthesia: a Randomized, Placebo-controlled Trial

Gangnam Severance Hospital1 site in 1 country72 target enrollmentNovember 1, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
General Anesthesia
Sponsor
Gangnam Severance Hospital
Enrollment
72
Locations
1
Primary Endpoint
Remimazolam dose for no response to voice
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

It is important to decrease the time-to-loss of consciousness and anesthetics dose of remimazolam for general anesthesia induction. We will evaluate the effect of binaural sound for general anestheia induction using remimazolam infusion.

Registry
clinicaltrials.gov
Start Date
November 1, 2023
End Date
October 30, 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hyun-Chang Kim

Clinical Associate Professor

Gangnam Severance Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients scheduled for generla anesthesia
  • Patients aged 20-60
  • Patients with American Society of Anesthesiologist physical status classification 1-2
  • Patients with ideal body weight 50-80 kg

Exclusion Criteria

  • Patients with hearing disability
  • Patients using opioids or sedatives in 1 week
  • Patients who are dependent for alcoholics or drugs
  • Patients with hypersensitivities to remimazolam
  • Patients with arrhythmia, cardiovascular disease, heart failure, or hypovolemia
  • Patients with liver failure

Outcomes

Primary Outcomes

Remimazolam dose for no response to voice

Time Frame: At anesthesia day 0

Remimazolam dose for no response to voice will be measured at anesthesia day 0.

Secondary Outcomes

  • Remimazolam dose for patient state index 50(At anesthesia day 0)
  • Patient state index electroencephalography(At anesthesia day 0)
  • Anxiety level(At anesthesia day 0)
  • Remimazolam dose for no eye lash reflex(At anesthesia day 0)

Study Sites (1)

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